Table 1.

The characteristics of failure in five patients with relapse after supine isocentric craniospinal irradiation (CSI)

Patient number	Diagnosis	Treatment after surgery	Site and time of failure
1	Medulloblastoma	CSI 30 Gy, tumour bed 46 Gy plus chemotherapy	Primary site failure at 20 months
2	Medulloblastoma	CSI 30 Gy, tumour bed 55 Gy plus chemotherapy	T5–T6 spinal leptomeningeal metastasis at 24 months
3	Medulloblastoma	CSI 30 Gy, tumour bed 46.5 Gy plus chemotherapy	Primary site failure at 10 months
4	Ependymoma	CSI 30 Gy, tumour bed 60 Gy plus chemotherapy	Primary site progression at 3 months
5	Teratoma	CSI 30 Gy, tumour bed 60 Gy plus chemotherapy	T12–L1 spinal leptomeningeal metastasis at 18 months