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. 2016 Nov 28;6:37498. doi: 10.1038/srep37498

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Copyright © 2016, The Author(s)

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The impacts of gender-associated risk stratified by age (A) and age-sex interaction (B) on the development of cirrhosis in multivariate logistic regression models. Multivariate analyses indicated that the risk for cirrhosis started to accelerate at the age of 50 years in women, gradually approached the risk of men at the ages 60–69, and eventually overtook that in men after 70 years. NA: not available. ^*ORs were adjusted for sex ratio in general population. ^#ORs were adjusted for sex ratio in general population, HBV DNA level, HBeAg status, and levels of AST and ALT.