Table 1. Characteristics of the registered CHB patients.
| Non-cirrhotic CHB |
Cirrhotic CHB |
|||||
|---|---|---|---|---|---|---|
| Total n = 14,508 | Male n = 10,290 | Female n = 4218 | Total n = 3301 | Male n = 2414 | Female n = 887 | |
| Age, year | 40 (32, 50) | 40 (32, 48) | 40 (31, 52) | 51 (43, 59) | 50 (42, 58) | 56 (48, 62) |
| HBeAg positive rate, % | 3761 (56.8%) | 2684 (55.9%) | 1077 (59.2%) | 494 (44.4%) | 363 (41.8%) | 131 (53.5%) |
| HBV DNA, log IU/ml | 3.64 (2.30, 6.05) | 3.66 (2.30, 5.94) | 3.60 (2.30, 6.24) | 2.58 (0, 4.79) | 2.63 (0, 4.84) | 2.56 (0, 4.49) |
| PLT count, ×109/L | 172.0 (133.0, 210.0) | 169.0 (131.0, 208.0) | 179.0 (136.0, 220.0) | 94.0 (59.0, 139.0) | 97.0 (63.0, 143.0) | 84.0 (52.1, 133.0) |
| ALT, IU/mL | 35.0 (22.0, 66.1) | 38.0 (24.0, 70.0) | 27.0 (17.0, 55.4) | 32.1 (23.0, 49.0) | 34.0 (24.0, 49.8) | 28.9 (19.9, 45.0) |
| AST, IU/mL | 30.0 (22.5, 48.7) | 30.3 (23.0, 49.0) | 28.0 (20.7, 47.0) | 32.6 (22.0, 51.0) | 33.0 (23.0, 50.0) | 32.0 (20.0, 52.0) |
| Albumin, g/L | 45.1 (42.0, 47.4) | 45.6 (42.4, 47.8) | 44.0 (41.2, 46.3) | 40.7 (34.0, 45.6) | 41.4 (34.5, 46.0) | 38.6 (32.9, 44.0) |
Bilirubin,  mol/L |
13.8 (10.5, 18.5) | 14.6 (11.2, 19.5) | 12.1 (9.2, 15.4) | 19.0 (13.2, 28.7) | 19.2 (13.5, 29.2) | 17.8 (12.6, 26.5) |
| CHE, IU/L | 8058.0 (6633.5, 9590.5) | 8426.5 (6788.0, 9891.0) | 7595.0 (6222.0, 8692.0) | 4868.5 (3039.5, 7108.0) | 4803.0 (3043.0, 7277.0) | 4877.0 (2973.0, 6615.5) |
| ALP, U/L | 72.0 (59.0, 91.0) | 75.0 (61.0, 92.0) | 66.0 (54.0, 86.0) | 86.0 (67.0, 117.0) | 86.0 (68.0, 117.0) | 87.0 (64.1, 117.0) |
| GGT, U/L | 26.0 (17.0, 47.3) | 30.0 (20.0, 55.1) | 18.0 (13.0, 31.2) | 45.0 (25.3, 80.0) | 49.0 (28.0, 87.0) | 36.0 (22.0, 63.0) |
Cr,  mol/L |
71.6 (61.0, 81.5) | 75.0 (67.0, 84.0) | 55.0 (49.0, 63.7) | 69.0 (58.0, 80.0) | 72.3 (64.0, 83.0) | 55.3 (48.0, 67.0) |
| Cholesterol, mmol/L | 4.3 (3.8, 5.1) | 4.3 (3.7, 5.1) | 4.5 (3.9, 5.1) | 3.6 (2.9, 4.4) | 3.7 (3.0, 4.5) | 3.6 (2.9, 4.3) |
| Triglyceride, mmol/L | 1.1 (0.8, 1.7) | 1.2 (0.8, 1.8) | 1.0 (0.7, 1.4) | 0.9 (0.6, 1.3) | 0.9 (0.7, 1.3) | 0.8 (0.6, 1.1) |
| PTA, % | 102.0 (88.0, 118.0) | 101.0 (87.0, 117.0) | 103.0 (90.0, 120.0) | 74.0 (59.0, 90.0) | 72.0 (58.0, 89.0) | 76.0 (63.3, 92.0) |
| INR, ratio | 1.0 (0.9, 1.1) | 1.0 (0.9, 1.1) | 1.0 (0.9, 1.0) | 1.1 (1.0, 1.3) | 1.2 (1.0, 1.3) | 1.1 (1.0, 1.3) |
Data were presented by median (lower quartile, upper quartile).
CHB, chronic hepatitis B; PLT, platelet; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CHE, cholinesterase; ALP, alkaline phosphatase; GGT, gamma glutamyltransferase; Cr, creatinine; PTA, prothrombin activity; INR, international normalized ratio of prothrombin time.