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. 2016 Nov 28;6:37853. doi: 10.1038/srep37853

Figure 1. Dynamics of the model over 30 days with antibiotic therapy administered at a daily dose of 23 μg/ml for the first 10 days.

Figure 1

(a) Stochastic simulations of the population dynamics of both susceptible (blue) and resistant (green) bacteria with the deterministic dynamics (bold) overlaid. 5000 simulations were run producing a success rate of eradicating the infection of 99.8% (95% CI: 99.6, 99.9). (b) Simulation of the concentration profile of antibiotic present within the system over the 30 day duration. The MIC lines indicate the concentration of antibiotic required to inhibit the growth of the respective bacterial strain, 16 μg/ml for susceptible bacteria and 32 μg/ml for resistant bacteria. A maximum antibiotic concentration of 60 μg/ml is observed on Day 10.