Table 3. Comparison of dosage vectors produced by the GA with stochastic modelling for maximum daily doses of 60, 50 and 40 μg/ml and the case where all 184 μg/ml of antibiotic is used.
Dosage Vector | Total Antibiotic | Success Rate (%) [95% CI, n = 5000] | Time to Eradication (days) [95% CI] | |
---|---|---|---|---|
S1 | (60, 19, 17, 16, 19,18, 0, 0, 0, 0) | 149 μg/ml | 96.9 [96.2, 97.2] | 4.14 [4.09, 4.20] |
S2 | (50, 25, 24, 20, 20,12, 0, 0, 0, 0) | 151 μg/ml | 98.4 [97.7, 98.5] | 4.23 [4.18, 4.31] |
S3 | (40, 27, 21, 22, 23,12, 18, 0, 0, 0) | 163 μg/ml | 97.1 [96.6, 97.5] | 5.03 [4.96, 5.11] |
S4 | (60, 22, 22, 22, 18,15, 14, 11, 0, 0) | 184 μg/ml | 99.7 [99.5, 99.8] | 3.94 [3.89, 3.99] |
n = 4845, 4920, 4855 and 4985 for time to eradication of S1, S2, S3 and S4 respectively.