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. 2016 Nov 28;6:37462. doi: 10.1038/srep37462

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Copyright © 2016, The Author(s)

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(A) CDPs were cultured on EL08 stromal cells for 5 days and progenies of the CDP were tracked continuously. Pedigrees were segregated according to their cell fates. The numbers of generations in each pedigree are shown as symbols (CCR9^high pDC fate, n = 11 vs. only Siglec H⁺ CCR9^low precursor fate, n = 18). Median numbers of generations are indicated by lines. *p = 0.0055, unpaired t-test. (B) The numbers of pedigrees with the indicated number of generations are shown for pedigrees with CCR9^high pDC fate (white columns) and only Siglec H⁺ CCR9^low precursor fate (grey columns). (C) The cell life times of all dividing cells in pedigrees with CCR9^high pDC fate (n = 153 cells) and Siglec H⁺ CCR9^low precursor fate (n = 134 cells) are shown (ns: not significant, unpaired t-test).