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. 2016 Nov 28;6:37372. doi: 10.1038/srep37372

Figure 2. Genetic organization of the ICEs in this study.

Figure 2

The upper indicate backbone, represents the 52 conserved core genes of the SXT/R391 family ICEs. Below the common structure, indicate five hotspots (HS1–5) and two variable (III and IV) regions of the fourteen ICEs (except for ICEPmiCHN3277, which was incompletely assembled). Drug-resistance gene (red triangle); the restriction-modification system (RM) (yellow triangle); β-lactamase encoding gene (pink triangle); mercury resistance gene (orange triangle); other genes (blue triangle). Detailed annotated genes from all fifteen ICEs are listed in Supplementary Table S3.