Table 2. Top 20 shared DEGs identified in the meta-analysis.
| EntrezID | Gene symbol | Gene Name | Combined ES | Adjusted p-value |
|---|---|---|---|---|
| Top 10 Over-expressed Genes | ||||
| 678 | ZFP36L2 | ZFP36 ring finger protein-like 2 | 2.2679 | 8.26E-06 |
| 55692 | LUC7L | LUC7 like | 1.7633 | 9.99E-05 |
| 22861 | NLRP1 | NLR family, pyrin domain containing 1 | 1.6398 | 2.28E-11 |
| 440270 | GOLGA8B | Golgin A8 family member B | 1.543 | 0.001225 |
| 5878 | RAB5C | RAB5C, member RAS oncogene family | 1.5252 | 0.010788 |
| 1606 | DGKA | Diacylglycerol kinase alpha | 1.4978 | 0.000458 |
| 9057 | SLC7A6 | Solute carrier family 7 member 6 | 1.4452 | 0.018486 |
| 81669 | CCNL2 | Cyclin L2 | 1.4413 | 0 |
| 55696 | RBM22 | RNA binding motif protein 22 | 1.4279 | 1.63E-05 |
| 923 | CD6 | CD6 molecule | 1.4242 | 0.00429 |
| Top 10 Under-expressed Genes | ||||
| 7504 | XK | X-linked Kx blood group | −1.6059 | 9.19E-08 |
| 475 | ATOX1 | Antioxidant 1 copper chaperone | −1.4773 | 1.99E-06 |
| 8804 | CREG1 | Cellular repressor of E1A stimulated genes 1 | −1.4133 | 0.001229 |
| 5627 | PROS1 | Protein S (alpha) | −1.3574 | 0.000767 |
| 10855 | HPSE | Heparanase | −1.336 | 0.022878 |
| 4501 | MT1X | Metallothionein 1X | −1.3259 | 1.85E-06 |
| 9446 | GSTO1 | Glutathione S-transferase omega 1 | −1.2905 | 0 |
| 4860 | PNP | Purine nucleoside phosphorylase | −1.2799 | 0 |
| 2281 | FKBP1B | FK506 binding protein 1B | −1.262 | 0.001107 |
| 51327 | AHSP | Alpha hemoglobin stabilizing protein | −1.2479 | 1.30E-09 |
Genes were ranked based according to the Standardized difference, also known as effect size. The corresponding p-values are adjusted, based on the false discovery rate using the Benjamini–Hochberg procedure used to select DE genes obtained in each meta-analysis. Combined ES: Combined Effect.