Table 1. Effect of BA on scores changes of renal histology variable in normal and diabetic mice .

Groups	Histopathological criteria
	Normal	Brush border loss	Tubular dilation	Vasodilatation	Infiltration of leukocytes
Control	98.9%	0.6±0.9	0±0	0±0	0±0
Diabetes	74.2±9.2#	8.5±1.8#	2.5±0.6#	6.4±1.1#	2.6±0.4#
Diabetes+BA10	89.8±7.5*	3.9±0.5*	1.8±1.0*	1.7±0.3*	0±0*
Diabetes+BA20	91.4±8.3*	3.5±1.1*	1.6±0.2*	1.5±0.2*	0±0*
Diabetes+BA40	91.7±7.1*	3.8±0.9*	1.7±0.4*	1.6±0.3*	0±0*
Diabetes+ metformin	91.6±9.3*	3.6±0.8*	1.5±0.4*	1.4±0.6*	0±0*

Abbreviation: BA; betulinic acid.

Data are shown as mean± SEM, n=10, (*P<0.05) when compared with diabetes group, (#P<0.05) when compared with control group.