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. Author manuscript; available in PMC: 2016 Nov 28.
Published in final edited form as: Facial Plast Surg Clin North Am. 2015 Jun 12;23(3):273–283. doi: 10.1016/j.fsc.2015.04.001

Table 2.

Summary of systematic reviews and meta-analysis retrieved from journals in facial plastic surgery

Author, Year Scope Review Question Outcomes Conclusions
Wee et al,13
2015
Rhinoplasty Evaluate complications related to
autologous rib cartilage
rhinoplasty
Nasal complications, donor-site
morbidity, and revision surgery
Long-term complications and
donor-site morbidity rates
associated with autologous rib
cartilage use in rhinoplasty were
low. Because of limitations future
studies are needed.
Paleri et al,18 2014
Microvascular Evaluated impact of vascularized
tissue on fistula rate after
laryngectomy reconstruction
Fistula rate Flap reconstruction/reinforcement
with vascularized tissue reduced
their risk of pharyngocutaneous
fistula by approximately one-third.
Rhee et al,19
2014
Rhinoplasty Define symptomatic, normative,
and postoperative values for
nasal obstruction
Nasal obstruction assessed with
VAS and NOSE
VAS and NOSE can be used as a
clinically meaningful measure of
successful surgical outcomes.
da Silva et al,8
2014
Perioperative To determine the effects, including
safety, of perioperative
administration of corticosteroids
for preventing complications
following facial plastic surgery
in adults
Ecchymosis and edema Limited evidence that corticosteroids
decrease ecchymosis and edema.
There is little evidence regarding
the safety of this intervention.
Cheung et al,20
2013
Trauma Determine safety and efficacy of
endoscopic management of
isolated orbital floor fractures
Resolution of diplopia and
enophthalmos, postoperative
complications
Reconstruction of orbital floor
fractures through an endoscopic
approach seems to be safe and
effective.
Morris & Kellman,21
2014
Trauma
(antibiotics)
Studied role of prophylactic
antibiotics in the management
of facial fractures
Postoperative infection rate Risk of infection in patients with
mandibular fractures is reduced
with use of prophylactic antibiotics
from time of injury to completion of
the perioperative course.
Picavet et al,22
2011
BDD Assessment of screening tools for
BDD in cosmetic surgery setting
BDD questionnaire-dermatology
version, dysmorphic concern
questionnaire
Despite high prevalence of BDD in
cosmetic surgery, little is known
about these tools in the cosmetic
surgery setting. Further research is
needed on the prevalence of BDD in
cosmetic surgery and impact of BDD
on treatment outcomes.
André et al,23
2009
Rhinoplasty Studied the relationship between
subjective and objective
evaluation of the nasal airway
Rhinomanometry, acoustic
rhinometry, patient-reported
outcomes
Patients’ subjective nasal obstruction
does not correlate well with
rhinomanometry and acoustic
rhinometry. There is thus little
evidence for routine use of
rhinomanometry or acoustic
rhinometry for quantifying surgical
results in clinical rhinologic practice.
Spielmann et al,24
2009
Rhinoplasty Evaluate surgical treatment
strategies for nasal valve collapse
Subjective symptom relief,
cosmetic outcome, objective
measurements of nasal airway
patency
No randomized controlled trials on
nasal valve surgery were identified.
Reporting of long-term outcomes is
limited. There is uncertainty
regarding evidence base for choice
of specific technique and duration
of benefit.
Nash et al,25
2010
Trauma/facial
nerve
Evaluate impact of early surgical
intervention vs steroid
administration/observation
House-Brackmann scale The available evidence does not
clearly indicate whether surgical vs
nonsurgical intervention achieves
most favorable outcome for facial
paralysis after trauma.
Rhee & McMullin,26
2008
Measurement Identify outcome instruments
specific for facial plastic surgery
interventions and conditions
Outcome instruments validation Validated outcome measures are
available for common facial plastic
surgery conditions. Challenges
remain in harmonizing and
standardizing the different
measures to reach clinically
meaningful assessments of
outcomes.
Rhee et al,27 2008 Rhinoplasty Critical review of evidence
supporting functional
rhinoplasty or nasal valve repair
Validated patient-reported
outcome measures
Level 4 evidence supports the efficacy
of functional rhinoplasty for
treatment of nasal obstruction
arising from nasal valve collapse.
Further studies with standardized
objective outcome measures and
comparison cohorts are needed.
Leventhal et al,28
2006
Wound healing Determine treatments that can
improve keloid and hypertrophic
scars
Assessment of keloid and
hypertrophic scars
Most treatments for keloidal and
hypertrophic scarring offer minimal
likelihood of improvement.
Koch & Perkins,29
2002
Rhytidectomy/laser Evaluate the safety of combining
carbon dioxide laser resurfacing
with full-face rhytidectomy
Rate of postoperative
complications
Simultaneous rhytidectomy and
carbon dioxide laser resurfacing can
safely provide a dual cosmetic
benefit for aesthetic rejuvenation.

The journals JAMA Facial Plastic Surgery, Laryngoscope, JAMA Otolaryngology, and Otolaryngology – Head & Neck Surgery were searched using publication type limit to “review,” “systematic review,” or “meta-analysis.” Cochrane library was also searched for related reviews. The titles and abstracts were first screened, and then two reviewers independently identified eligible studies (systematic review or meta-analysis in facial plastic surgery). Subsequently, the data were extracted from each eligible study using standardized form and summarized.

Abbreviations: BDD, body dysmorphic disorder; NOSE, Nasal Obstruction Symptom Evaluation scale; VAS, visual analog scale.

Data from Refs.8,13,1829