Table 1. Estimated β- and α- cells area at e14.5.
Ins+ cell area (μm2) | Gluc+ cell area (μm2) | Ins+ cell area/Gluc+ cell area | |
---|---|---|---|
Non transgenic | 52 ± 14 | 46 ± 12 | 1.13(*) |
Nkx3.2-Cre;Ptchf/f | 48 ± 14 | 42 ± 11 | 1.15(*) |
Cell area (Mean ± SD) was measured in non-transgenic and Nkx3.2-Cre;Ptchf/f littermate e14.5 embryos. n = 50 cells. (*) p value: p < 0.05, between β-cell and α-cell area within mouse group, determined using Student’s t-test. No significance differences were detected between cells area in non-transgenic and transgenic embryos. Ins = insulin; Gluc = glucagon.