Figure 8. Extracellular RNA-mediated pneumococcal infection is diminished after RNase1 treatment.
(A,B) A549 cells were preincubated with eRNA (5 μg) and infected with SpΔply pneumococci in the absence or presence of RNase1 (1 and 10 ng). Pneumococcal host-cell adherence to (A) and internalization (B) into A549 cells were tested using antibiotic protection assay. Data represent mean values ± SEM; n = 3; **p ≤ 0.01.