Table 1.
Baseline demographic characteristics, ARDS predisposing factors, and mortality.
| Demographic data | Totally, n = 24 | ARDS, n = 14 | Non-ARDS, n = 10 | p-Value |
|---|---|---|---|---|
| Age, years | 54 ± 17 | 55 ± 15 | 53 ± 19 | 0.7 |
| Women, n (%) | 3 (12) | 2 (14) | 1 (10) | 0.8 |
| BMI | 26.4 ± 4.6 | 24.7 ± 2.8 | 27.2 ± 3.2 | 0.4 |
| Comorbidities | ||||
| Hypertension, n (%) | 7 (29) | 4 (29) | 3 (30) | 0.1 |
| Diabetes mellitus, n (%) | 4 (17) | 2 (14) | 2 (20) | 0.6 |
| COPD, n (%) | 3 (12) | 1 (7) | 2 (20) | 0.4 |
| Conditions predisposing for ARDS | ||||
| Pneumonia, n (%) | 11 (46) | 6 (42) | 5 (50) | 0.7 |
| Sepsis, n (%) | 7 (29) | 4 (29) | 3 (30) | 0.9 |
| Pancreatitis, n (%) | 5 (21) | 4 (29) | 1 (10) | 0.3 |
| Massive transfusions, n (%) | 1 (4) | 0 | 1 (10) | 0.2 |
| Severity scores | ||||
| SOFA, median (range) | 4 (3.4–6.1) | 5 (4.6–7.2) | 3 (2.1– 4.9) | 0.04 |
| APACHE II, median (range) | 23 (19–28) | 25 (22–28) | 21 (19–24) | 0.03 |
| LIPS median (range) | 5.8 (0.3–13) | 8.1 (3–13) | 4.9 (0.3–9) | 0.01 |
| Coagulation status | ||||
| INR | 1.18 ± 0.4 | 1.2 ± 0.6 | 1.12 ± 0.15 | 0.03 |
| PLT (109/l) | 172 ± 56 | 136 ± 47 | 213 ± 31 | 0.003 |
| Fibrinogen (mg/dl) | 283 ± 71 | 261 ± 96 | 312 ± 63 | 0.02 |
| ICU stay and mechanical ventilation | ||||
| ICU days, n | 12 ± 5 | 14 ± 7 | 11 ± 4 | 0.7 |
| Ventilator-free days, n | 5 ± 3 | 4 ± 2 | 7 ± 4 | 0.4 |
| Mortality | ||||
| Hospital, n (%) | 6 (25) | 4 (29) | 2 (20) | 0.1 |
| 30-day, n (%) | 6 (25) | 4 (29) | 2 (20) | 0.1 |
Data are presented as mean ± SD, number (n), or median (range).
APACHE II, chronic health evaluation score; ARDS, acute respiratory distress syndrome; BMI, body mass index; ICU, intensive care unit; INR, international normalized ratio; LIPS, lung injury prediction score; n, number of patients; PLT, platelets; %, percent; range, lowest and highest value; SOFA, sequential organ failure assessment score.