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. 2016 Nov 5;129(21):2567–2575. doi: 10.4103/0366-6999.192776

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Copyright: © 2016 Chinese Medical Journal

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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A1, A2, and A3 show control groups at 2, 4, and 8 weeks, respectively. B1, B2, and B3 show treatment groups at 2, 4, and 8 weeks, respectively, after shock wave treatment. B1 shows more plentiful collagen, osteoblasts, and ossification than A1. OPG levels were shown to increase in response to the treatment. OPG was mainly expressed in myeloid tissues of the marrow cavity at 4 weeks after the treatment, as shown in A2 and B2. B3 shows that the reconstruction of the trabecular bone had basically been completed and fiber callus disappeared at 8 weeks. The reparative process was not adequately completed, and OPG remained visible in the marrow cavity (immunohistochemical staining, Original magnification ×200: SP method). OPG: Osteoprotegerin; SP: Streptavidin - peroxidase.