Accelerated diabetic retinopathy (DR) in ataxia telangiectasia mutated (ATM)−/−→ wild type (WT) chimeras. (A): Isolated mouse retinas were trypsin digested and stained with PAS-hematoxylin stain, top panel showing representative pictures of retinal trypsin digests from respective groups. Red arrows showing acellular capillaries as a marker of DR. Scale bar = 50 μm (B): Bar chart showing quantification of numbers of acellular capillaries. WT (n = 6), WT→WT (n = 8) WT+ STZ (n = 5), ATM−/−→WT (n = 5) WT→WT + STZ (n = 9), ATM−/−→WT (n = 5) Statistical Test- One way analysis of variance followed by Student’s Newman Keul Test. Abbreviations: ATM, ataxia telangiectasia mutated; STZ, streptozotocin; WT, wild type.