Increase in retinal inflammation of ataxia telangiectasia mutated (ATM)−/−→ wild type (WT) chimeric animals. qRT-PCR was performed on isolated retinas, bar chart showing mRNA expression of a variety of retinal inflammatory markers (HIF-1α, PDGF-β, vascular endothelial growth factor [VEGF], Glial fibrillary acidic protein [GFAP], CD45, Lipocalin-2 [LCN-2], and CCL2). WT (n = 5), WT→WT (n = 8) WT+ STZ (n = 4), WT→WT + STZ (n = 13) ATM−/−→WT (n = 5), ATM−/−→WT (n = 5). Statistical test-one way analysis of variance followed by Student’s Newman Keul Test. Abbreviations: ATM, ataxia telangiectasia mutated; CCL2, The chemokine (C-C motif) ligand 2; GFAP, Glial fibrillary acidic protein; HIF-1α, Hypoxia-inducible factor 1-alpha; LCN-2, Lipocalin-2; PDGF-β, Platelet-Derived Growth Factor Beta; STZ, streptozotocin; VEGF, vascular endothelial growth factor; WT, wild type.