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. 2016 Jul 19;1(2):136–148. doi: 10.1002/btm2.10018

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© 2016 The Authors. Bioengineering & Translational Medicine is published by Wiley Periodicals, Inc. on behalf of The American Institute of Chemical Engineers

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Bridge implantation and lentivirus delivery do not increase immune cell infiltration. The infiltration of immune cells into the injury site after hemisection spinal cord injury were quantified as a percentage of total cells by flow cytometry at days 7 and 28 (n = 9–15 mice). A mock implantation consisting of the hemisection injury without bridge implantation (no bridge) was compared to bridge implantation, luciferase control lentivirus (vCtrl) loaded bridge implantation, and IL‐10 lentivirus (vIL‐10) loaded bridge implantation. Statistical analysis was completed using a two‐way ANOVA with a Šidák correction for multiple comparisons. Significant differences between days 7 and 28 notated with ** (p <.01) or * (p <.05)