Figure 3.

IL‐10 delivery from bridge reduces neutrophil infiltration. The infiltration of immune cell sub‐populations into the injury site was investigated for no bridge, bridge, luciferase control lentivirus (vCtrl) loaded bridges, and IL‐10 lentiviral (vIL‐10) loaded bridges (n = 6–21 mice). Infiltration of sub‐populations of innate immune cells were quantified by flow cytometry at day 7 and day 28 including (A) CD11c⁺ dendritic cells, (B) F4/80⁺ macrophages, and (C) Gr‐1⁺ neutrophils. Statistical analysis completed using a one‐way ANOVA with Tukey's post hoc test. Significantly different groups denoted by letter with “a” and “b” denoting statistical significance between the two groups p < .05 for Gr‐1 and p < .005 for all others