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. Author manuscript; available in PMC: 2016 Nov 29.
Published in final edited form as: Mucosal Immunol. 2016 Jan 27;9(5):1173–1182. doi: 10.1038/mi.2015.141

Figure 7.

Figure 7

Effect of IL-1Ra against lethal influenza challenge. C57BL/6J mice were infected with mouse-adapted influenza strain PR8 (∼7500 TCID50, i.n.). Mice received vehicle (saline; i.v.), Eritoran (E5564; 200 μg/mouse; i.v.), or the IL-1Ra (150 μg/mouse; i.v.) from day 2 to day 6 post-infection. Survival (top panel) and clinical scores (bottom panel) were monitored daily for 14 days. Data shown is combined from 2 separate experiments (5 mice/treatment group/experiment).