Table 2.
Univariable & Multivariable analysis of 302 patients with Sporadic Metastatic Colorectal Cancer.
| Number | Univariable Analysis | Multivariable Analysis | ||||
|---|---|---|---|---|---|---|
| Factor | 5 year survival | P value | Hazard Ratio | 95% Confidence Intervals | P value | |
| Extrahepatic disease: Yes | 154 | 12% | <0.001 | 1.00 | 0.73 – 1.39 | 0.96 |
| No | 148 | 28% | ||||
| Before 2000 | 123 | 7% | <0.001 | 1.55 | 1.19 – 2.01 | 0.001 |
| After 2000 | 179 | 28% | ||||
| Gender: Male | 131 | 14% | 0.78 | |||
| Female | 171 | 24% | ||||
| Site of primary tumor: Rectum | 66 | 16% | 0.12 | |||
| Left colon | 153 | 24% | 0.91 | 0.62 – 1.33 | 0.64 | |
| Right colon | 82 | 15% | 0.90 | 0.66 – 1.21 | 0.48 | |
| KRAS mutant: Yes | 19 | 31% | 0.02 | |||
| No | 37 | 54% | ||||
| HAIP Chemotherapy: Yes | 79 | 30% | <0.001 | 0.97 | 0.67 – 1.41 | 0.94 |
| No | 223 | 15% | ||||
| Liver resection: Yes | 103 | 43% | <0.001 | 3.65 | 2.52 – 5.28 | <0.001 |
| No | 197 | 7% | ||||
| Resection of primary tumor: Yes | 249 | 23% | <0.001 | 2.01 | 1.40 – 2.88 | <0.001 |
| No | 52 | 0% | ||||
| Nodal disease in primary tumor: Yes | 201 | 22% | ||||
| No | 36 | 34% | ||||
| Pregnant at Diagnosis: Yes | 21 | 26% | 0.42 | |||
| No | 281 | 19% | ||||
| Inflammatory bowel disease: Yes | 14 | 14% | 0.10 | |||
| No | 288 | 20% | ||||