Fig 1. Animal model and electric field distribution After sterile thoracotomy, IRE was applied to the anterior myocardium located to the left of the lower part of the left anterior descending artery (Fig 1.1 and Fig 1.2).

Electric field distribution induced by two-needle electrodes and a 500 volt pulse are illustrated in Fig 1.3. Note that electric field intensity is concentrated in the plane between the two electrodes.