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. 2016 Nov 28;11(11):e0166956. doi: 10.1371/journal.pone.0166956

Fig 5. Effect of whole-body Pten haplodeficiency on metabolic parameters.

Fig 5

a. Body weight, b. Liver weight c. Liver TAG in μg/g tissue d. Fatty acid synthase (FAS) and e. Pten expression. Mice (BW: (WT (ND, n = 6; HFD, n = 9), Pten +/- (ND, n = 9; HFD, n = 10)), Liver weight: (WT(ND, n = 6; HFD, n = 9), Pten +/- (ND, n = 9; HFD, n = 10)), TAG: (WT(ND, n = 5; HFD, n = 9), Pten +/- (ND, n = 8; HFD, n = 9)), FAS: (WT (ND, n = 6), Pten +/- (ND, n = 6)) and Pten: (WT (ND, n = 4), Pten +/- (ND, n = 4))) had been fed with ND or HFD for 20 weeks. Data are presented as mean ± SEM. * p≤0.05 and ** p≤0.01.