Table 2. Apoptotic and mitotic cells after treatment with insulin and the Pten-inhibitor VO-OHpic.
Treatment Groups | Apoptosis | Mitosis |
---|---|---|
Control | 1 ± 0.23 | 1 ± 0.1 |
VO-OHpic | 0.83 ± 0.15 | 1.07 ± 0.19 |
10nM Insulin | 0.56 ± 0.2 | 1.29 ± 0.19 |
100nM Insulin | 1.14 ± 0.18 | 1.18 ± 0.14 |
VO-OHpic + 10 nM Insulin | 1.11 ± 0.19 | 1.05 ± 0.17 |
VO-OHpic + 100nM Insulin | 1.14 ± 0.41 | 1.18 ± 0.21 |
Data are shown as mean fold change compared to control (± SEM) and are calculated from evaluated numbers/1000 cells from 4 independent experiments.