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. 2016 Nov 28;11(11):e0167087. doi: 10.1371/journal.pone.0167087

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© 2016 Wadman et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 5 — Levels of SMN2-FL and SMN2-Δ7 in relation to SMN2 copy number in blood (Panel A; KW SMN2-FL p = 0.7; KW SMN2-Δ7 p = 0.3) and fibroblasts (Panel B; KW SMN2-FL p = 0.3; KW SMN2-Δ7 p = 0.09) from patients with SMA. Data shown are normalized to the geometric mean (= GM) of GAPDH- and 18S-reference genes. Boxplot elements represent: median (line in the middle), 1^st en 3^rd quartile (bottom and top of the box), highest case with 1.5 time inter-quartile range (bottom and top whisker) and outliers (dots and asterisks). SMN2-D7 = SMN2-Δ7.