Table 4. Enriched (enrichment score = 5.36) cluster of Gene Ontology (GO) biological process (BP), molecular function (MF) Functional Annotation Tool (FAT) categories among the genes significantly differentially expressed (FDR-adjusted P-value < 0.05) between mice from Control (C) and High (H) activity genotypes.

Category	Term	Count	P-value	FDR P-value
Score	= 5.36
MF	GO:0022843~voltage-gated cation channel activity	13	6.43E-09	8.50E-06
MF	GO:0022832~voltage-gated channel activity	14	3.26E-08	4.31E-05
MF	GO:0005244~voltage-gated ion channel activity	14	3.26E-08	4.31E-05
MF	GO:0005261~cation channel activity	15	2.21E-07	2.92E-04
BP	GO:0030001~metal ion transport	19	3.35E-07	5.21E-04
BP	GO:0006812~cation transport	20	6.92E-07	1.08E-03
MF	GO:0005249~voltage-gated potassium channel activity	10	7.05E-07	9.32E-04
MF	GO:0046873~metal ion transmembrane transporter activity	15	1.45E-06	1.92E-03
MF	GO:0022836~gated channel activity	14	5.61E-06	7.42E-03
MF	GO:0005267~potassium channel activity	10	6.46E-06	8.54E-03
MF	GO:0005216~ion channel activity	15	1.24E-05	1.63E-02
MF	GO:0022838~substrate specific channel activity	15	1.75E-05	2.31E-02
MF	GO:0015267~channel activity	15	2.04E-05	2.70E-02
MF	GO:0022803~passive transmembrane transporter activity	15	2.04E-05	2.70E-02
BP	GO:0006811~ion transport	21	2.13E-05	3.31E-02
MF	GO:0030955~potassium ion binding	9	2.64E-05	3.49E-02
BP	GO:0006813~potassium ion transport	10	2.89E-05	4.49E-02
MF	GO:0031420~alkali metal ion binding	11	4.72E-05	6.23E-02
BP	GO:0015672~monovalent inorganic cation transport	12	2.04E-04	3.17E-01