. 2016 Nov 28;11(11):e0167131. doi: 10.1371/journal.pone.0167131

Table 3. Effect of SR on serum lipid profile, glycosylated haemoglobin, membrane bound enzymes, C-reactive proteins and troponin levels of T2D rats.

Parameters	Group I	Group II	Group III	Group IV	Group V
Total cholesterol (mg/dl)	92.33± 6.54	156.48 ± 13.21^#	118.67 ± 9.87^*	112.89 ± 6.21^**	105.50 ± 8.62^**
HDL cholesterol (mg/dl)	31.21 ± 3.12	17.67 ± 2.11^#	25.43 ± 2.85	27.86 ± 2.09^*	27.98 ± 2.92^*
Triglycerides (mg/dl)	116.75 ± 14.56	202.37 ± 19.22^#	156.88 ± 17.65	138.76 ± 14.32^*	133.56 ± 15.67^*
LDL cholesterol (mg/dl)	37.78 ± 3.45	174.22 ± 9.67^#	61.47 ± 5.11^**	57.28 ± 4.98^**	50.81 ± 5.23^**
Glycosylated haemoglobin(mg/g haemoglobin)	0.32± 0.11	0.63 ± 0.25^#	0.41 ± 0.16	0.38 ± 0.07^*	0.34 ± 0.09^**
Lactate dehydrogenase (U/l)	187.08± 12.33	285.07 ± 21.15^#	218.56 ± 17.92^*	215.34 ± 18.50^*	202.58 ± 20.80^*
Creatine kinase (IU/mg of protein)	9.42 ± 1.45	19.05 ± 2.04^#	13.24 ± 1.01^*	12.67 ± 1.31^*	12.33 ± 1.29^**
C-reactive protein (mg/dl)	1.14 ± 0.48	3.01 ± 0.72^#	1.67 ± 0.35^**	1.41 ± 0.48^**	1.32 ± 0.29^**
Troponin I (ng/ml)	0.045 ± 0.014	0.087± 0.02^$	0.06 ± 0.017	0.048 ± 0.028^*	0.048 ± 0.033^*
Troponin T (ng/ml)	0.012 ± 0.002	0.027 ± 0.003^#	0.02 ± 0.007^*	0.017 ± 0.0008^**	0.015 ± 0.003^**

Data were expressed as mean ± SD (n = 6).

^$p< 0.05 compared with Group I

^#p< 0.01 compared with Group I

*p< 0.05 compared with Group II

**p< 0.01 compared with Group II.

Group I: Normal control; Group II: T2D control, Group III: T2D rats treated with SR (50 mg/kg, p.o.); Group IV: T2D rats treated with SR (100 mg/kg, p.o.); Group V: T2D rats treated with glibenclamide (1 mg/kg, p.o.).