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. 2016 Nov 28;11(11):e0167221. doi: 10.1371/journal.pone.0167221

Table 1. Pharmacokinetic parameters of verdinexor following a per os dose of 5 mg/kg in male ferrets.

PK parameters Unit Mean SD CV
Tmax h 0.361 0.241 66.7
Cmax ng/mL 1494 1053 70.5
Terminal T1/2 h 1.84 0.148 8.08
AUClast h*ng/mL 3506 1850 52.8
AUCINF h*ng/mL 3513 1845 52.5