Table 5.

Univariate and multivariate logistic regression analysis of predictors for late toxicity based on patients with follow-up time greater than 12 months.

Variable	All Patients				Oropharynx Patients
	Univariate		Multivariate		Univariate		Multivariate
	OR	P value	OR	P value	OR	P value	OR	P value
Age (≥71 vs. <71)	3.23	.01	3.11	.04	4.45	.009	3.74	.07
KPS (≤80 vs. >80)	1.24	.60			1.05	.93
T classification (T4 vs. T1–T3)	2.72	.02	1.97	.16	2.34	.12
N classification (N2–N3 vs. N0–N1)	1.18	.66			1.50	.44
Charlson index (≥2 vs. 0/1)	2.48	.04	1.45	.47	2.94	.08
Tobacco history >10 pack-year (yes vs. no)	1.33	.44			1.28	.58
Pre-RT trach (Yes vs. No)	6.91	.0006	4.55	.02	18.95	.002	20.67	.02
Drug
Cisplatin vs. 5FU/carboplatin	0.26	.001	0.40	.053	0.21	.002	0.32	.04
Cetuximab vs. 5FU/carboplatin	0.25	.046	0.17	.02	0.12	.049	0.04	.03

Abbreviations: 5FU = 5-fluorouracil; OR = odds ratio.