Table 2.

Results of gene-by-pesticide interaction analyses at the SNP level: top 10 SNP-pesticide interaction association signals.

SNP	Chr	Position (build 36)	Gene	Major Allele	Minor Allele	MAF	OR ratio	P value
rs67383717	9	97666369	LINC00476, upstream of ERCC6L2	C	A	0.469	0.29	2.4E-06
rs591486	9	97689867	ERCC6L2	A	G	0.467	0.30	2.7E-06
rs6851004	4	116951675	PGAM4P2, KRT18P21	T	A	0.246	4.06	1.3E-05
X6.90946408	6	90946408	BACH2	C	T	0.089	9.19	1.4E-05
X6.90949107	6	90949107	BACH2	A	G	0.089	9.18	1.4E-05
rs10013344	4	176146286	ADAM29	C	T	0.178	0.22	1.5E-05
rs10005382	4	176156562	ADAM29	C	G	0.179	0.23	1.5E-05
X6.90956325	6	90956325	BACH2	A	G	0.089	9.11	1.5E-05
rs539096	1	43845007	PTPRF	G	A	0.202	3.66	1.5E-05
rs6919587	6	90959852	BACH2	T	A	0.088	9.06	1.6E-05

MAF = minor allele frequency; OR ratio = ratio of odds ratios for allele effect in pesticide exposed vs. pesticide unexposed strata