Table 2.

IOP (in mmHg) changes in prednisolone versus difluprednate

Overall population	Categories
	Baselineb	TP1b	Δ from baselinea	TP2b	Δ from baselinea	≥21 mmHg overall and ≥10 mmHg increase at TP1c
Prednisolone (n=2,151)	14.7 (3.2)	15.6 (4.3)**	0.89 (4.6)**	14.2 (3.2)**	−0.49 (3.8)**	65 (3.02%)
Difluprednate (n=1,337)	14.6 (3.2)	16.2 (4.2)**	1.6 (4.7)**	14.6 (3.5)	0.04 (4.2)	59 (4.41%)
Δ mean IOP (95% CI)	−0.08 (−0.30, 0.13)	0.60 (0.30, 0.90)	0.21 (0.12, 0.31)	0.46 (0.23, 0.68)	0.16 (0.09, 0.23)	N/A
P-value	0.46	<0.001	<0.001	<0.001	<0.001	0.04

Notes: Data shown as mean (SD), mean change (SD), n (%), Δ mean (95% CI), or P-value.

^aP-values calculated using the analysis of covariance adjusted for baseline IOP.

^bP-values calculated using the Independent t-test.

^cP-values calculated using Fisher’s exact test at TP1.

^**P-value <0.001 comparing mean IOP change at each time point from baseline after multiple comparison adjustments.

Abbreviations: IOP, intraocular pressure; SD, standard deviation; TP1, 5–10 days postoperatively; TP2, 3–6 weeks postoperatively.