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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Neuropathol Appl Neurobiol. 2016 Aug 28;42(7):621–638. doi: 10.1111/nan.12337

Fig. 4. Immunostaining of endogenous markers of proliferation and neurogenesis in the human SGZ.

Fig. 4

Representative photomicrographs showing differences in immunostaining for Ki67 and DCX with age with the polymorphic layer to the right side in all images. Immunostaining shows the SGZ of a 0.3 year-old individual with (A) numerous Ki67+ cells with a nuclear staining pattern and (B) abundant DCX+ cells with predominantly somatic staining. A 1.3 year-old shows (C) a single Ki67+ cell and (D) numerous DCX+ cells with predominantly cytoplasmic staining. A16 year-old individual shows no Ki67+ cells (E) and a single DCX+ cell with dendritic and somatic staining (arrow). A 54 year-old individual shows the same pattern for both Ki67 (G) and DCX (H) as the 16 year-old individual. 400x magnification. Scale bar = 50μm.