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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Cell Immunol. 2016 Sep 4;310:141–149. doi: 10.1016/j.cellimm.2016.08.015

Fig. 4.

Fig. 4

Soluble factors from T cell responses with APCs induce ISG54 promoter activity in an IRF3 dependent fashion. Supernatants from Fig. 3 (A, B) or recombinant IFN-γ, poly I:C, or recombinant IFN-β (C) were incubated with RAW-Lucia (105) or IRF3KO RAW-Lucia (105) cells. Secreted luciferase from RAW-Lucia or IRF3KO RAW-Lucia was measured 24 h after incubation of these cells with T cell supernatants or recombinant IFN-γ, poly I:C, or recombinant IFN-β. Data are mean of relative luciferase activity ± SE, * indicates p< 0.05 using two-tailed Student’s t test. Results shown are representative of two independent repeats (n = 3)