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. Author manuscript; available in PMC: 2017 Dec 15.
Published in final edited form as: Life Sci. 2016 Oct 25;167:98–104. doi: 10.1016/j.lfs.2016.10.025

Fig. 5.

Fig. 5

Representative tracings of saline cystometry performed 7 days after bladder wall transfection in luciferase (control) and miR-132 plasmid transfected group (n=5) under urethane anesthesia. Panel B- Unpaired analysis of ICI demonstrated that overexpression of miR-132 in bladder leads to bladder overactivity in absence of acetic acid exposure (Unpaired student’s t test; **p<0.001). Panel C: Bladder wall transfection of miR-132 plasmid vector drastically upregulates the expression of miR-132, which consequently causes 5 fold upregulation of NGF and MCP-1 and two fold upregulation of sICAM-1 and Cx-43 genes relative to the control group transfected with luciferase plasmid (Unpaired student’s t test; *p<0.01)