Figure 4.

Time-dependent proliferation profile of unlabeled control and labeled iPSC-NP cells.

Notes: Proliferation curves of cells labeled with different concentrations of CZF and unlabeled control (A) and with PLL-coated γ-Fe₂O₃ and unlabeled control (B). Cell index represents cell viability, number, morphology and adhesion degree. Graphs represent results from three independent experiments ± SD (P<0.05; ● corresponds to difference between 5 μg Fe/mL and control; ■ corresponds to difference between 10 μg Fe/mL and control; * corresponds to difference between 15 μg Fe/mL and control).

Abbreviations: iPSC-NP, induced pluripotent stem cell-derived neural precursors; CZF, silica-coated cobalt zinc ferrite nanoparticles; PLL-coated γ-Fe₂O₃, poly-l-lysine-coated iron oxide superparamagnetic nanoparticles; SD, standard deviation.