Figure 8.

qRT-PCR analysis.

Notes: Unlabeled and labeled iPSC-NPs with CZF and PLL-coated γ-Fe₂O₃ were analyzed 2 weeks after the onset of differentiation. (A) The expression of the neural genes NES, TUBB3, SYP, and GFAP. (B) The expression of the mDN genes FOXA2, EN1, NURR1 and TH (*P<0.05). The average expression of studied markers in the unlabeled undifferentiated control was set as zero.

Abbreviations: qRT-PCR, quantitative real-time reverse transcription polymerase chain reaction; iPSC-NPs, induced pluripotent stem cell-derived neural precursors; CZF, silica-coated cobalt zinc ferrite nanoparticles; PLL-coated γ-Fe₂O₃, poly-l-lysine-coated iron oxide superparamagnetic nanoparticles; SYP, synaptophysin; GFAP, glial fibrillary acidic protein; mDN, midbrain dopaminergic neuron.