Table 3.
Relaxivity r2 in vitro of labeled cells
|
r2[s−1/mil cells/mL] ± SD
| ||||
|---|---|---|---|---|
| Nanoparticles | 5 μg Fe/mL | 10 μg Fe/mL | 15 μg Fe/mL | 1-week differentiation |
| CZF | 0.585±0.182 | 0.788±0.079 | 1.230±0.013 | 0.158±0.012 |
| PLL-coated γ-Fe2O3 | 0.965±0.139 | 1.50±0.098 | 3.316±0.824 | 0.128±0.002 |
Notes: r2 was measured in iPSC-NPs labeled with different concentrations of CZF and PLL-coated γ-Fe2O3 for 72 hours and homogenously suspended in gel phantoms. The table represents results from three independent experiments ± SD. Relaxivity r2 is related to 1×106 cells.
Abbreviations: CZF, silica-coated cobalt zinc ferrite nanoparticles; PLL-coated γ-Fe2O3, poly-l-lysine-coated iron oxide superparamagnetic nanoparticles; SD, standard deviation.