Table 3.
Multiple logistic regression models for the association of plasma fibrinogen concentration, financial strain, and an interaction parameter with plasma detectable HS-CTnT (n = 500).
| Model for detectable HS-CTnT | Mutually-adjusted exposure variables | OR | (95%CI) | P |
|---|---|---|---|---|
| 1. No further adjustments | Fibrinogen | 0.98 | (0.70 to 1.36) | 0.893 |
| Financial strain | 0.80 | (0.48 to 1.34) | 0.401 | |
| Interaction | 1.63 | (1.02 to 2.61) | 0.043 | |
| 2. Further adjusted for age and gender | Fibrinogen | 0.85 | (0.59 to 1.21) | 0.363 |
| Financial strain | 0.77 | (0.44 to 1.36) | 0.373 | |
| Interaction | 2.09 | (1.25 to 3.52) | 0.005 | |
| 3. Further adjusted for latest grade of employment | Fibrinogen | 0.83 | (0.58 to 1.19) | 0.318 |
| Financial strain | 0.75 | (0.42 to 1.32) | 0.312 | |
| Interaction | 2.07 | (1.23 to 3.47) | 0.006 | |
| 4. Further adjusted for CES-D, SF-36 mental health, SF-36 mental component, positive affect, and negative affect |
Fibrinogen | 0.84 | (0.58 to 1.21) | 0.354 |
| Financial strain | 0.77 | (0.43 to 1.40) | 0.397 | |
| Interaction | 2.07 | (1.23 to 3.51) | 0.007 | |
| 5. Further adjusted for smoking, alcohol consumption, and physical activity | Fibrinogen | 0.84 | (0.58 to 1.22) | 0.366 |
| Financial strain | 0.77 | (0.43 to 1.39) | 0.390 | |
| Interaction | 2.07 | (1.27 to 3.52) | 0.007 | |
| 6. Further adjusted for systolic and diastolic blood pressure, LDL, total cholesterol/HDL ratio, triglycerides, glycated haemoglobin, and BMI |
Fibrinogen | 0.80 | (0.55 to 1.16) | 0.236 |
| Financial strain | 0.78 | (0.43 to 1.44) | 0.432 | |
| Interaction | 2.07 | (1.20 to 3.55) | 0.009 | |
| 7. Further adjusted for HS-CRP, salivary cortisol, HS-IL-6, vWF, and MCP-1 | Fibrinogen | 0.72 | (0.47 to 1.09) | 0.117 |
| Financial strain | 0.80 | (0.43 to 1.47) | 0.475 | |
| Interaction | 2.11 | (1.22 to 3.67) | 0.008 | |
| 8. Further adjusted for Agatston coronary calcification score with 4 categories | Fibrinogen | 0.71 | (0.47 to 1.07) | 0.105 |
| Financial strain | 0.80 | (0.43 to 1.48) | 0.473 | |
| Interaction | 2.07 | (1.19 to 3.60) | 0.010 |
The OR pertaining to fibrinogen is for one standard deviation increase from the mean (Z score). Financial strain is a binary variable (1 vs 0). Interaction = multiplication between fibrinogen and financial strain.