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Thermal shift assays of the recombinant ligand binding domain of the PA5072/McpK chemoreceptor in the presence of bacterial carbon sources from the Biolog screen plate PM1. Shown are changes in Tm respective to the protein without ligand (38.7°C). A list of the individual compounds in this screen is provided in Supplementary Figure S1. Compounds that caused Tm shifts of at least 2°C are annotated.
