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. 2016 Nov 24;18(12):753–764. doi: 10.1016/j.neo.2016.10.011

Figure 6.

Figure 6

The effect of βIVb-tubulin silencing on pancreatic cancer cell chemosensitivity to vinblastine and vinorelbine. A-D) Bars represent the number of MiaPaCa-2 (A-B) or HPAFII (C and D) cell colonies (mean + S.E.M. as a % of untreated control siRNA [ns-siRNA] cells) that formed from low density seeding following transfection with ns-siRNA or βIVb-tubulin siRNA (βIVb-Tub siRNA) and 72 h culture in titrations of vinorelbine or vinblastine. Asterisks indicate significance relative to the 0 nM control for the same siRNA. Hashes indicate significance relative to the ns-siRNA control of the same drug dose (** or ##P ≤ .01, *** or ###P ≤ .001, **** or ####P ≤ .0001; n = 3).