Table 3.
Univariate and Multivariate Analyses of Potential Predictors of Malignant PNs
| A Training Set | A Testing Set | |||||
|---|---|---|---|---|---|---|
| Variable |
OR |
95% CI |
P |
OR |
95% CI |
P |
| Univariate analysis | ||||||
| Smoking pack-year | 1.22 | 1.01-1.26 | .002 | 1.26 | 1.19-1.32 | .003 |
| History of cancer | 1.35 | 1.30-1.40 | .021 | 1.34 | 1.28-1.43 | .023 |
| Nodule size | 1.16 | 1.12-1.22 | .001 | 1.17 | 1.11-1.22 | .010 |
| Nodule Location | 2.79 | 2.70-3.16 | .036 | 2.66 | 2.56-3.15 | .020 |
| Spiculation | 5.76 | 5.62-6.23 | <.001 | 5.68 | 5.59-6.58 | <.001 |
| Multivariate analysis | ||||||
| Smoking pack-year | 1.26 | 1.12-1.30 | .001 | 1.29 | 1.22-1.36 | .006 |
| Nodule size | 2.23 | 1.88-2.86 | .022 | 2.46 | 1.75-2.87 | .020 |
| Spiculation | 2.68 | 2.03-3.69 | .002 | 2.95 | 2.12-3.99 | .001 |