Table 3.
Characteristics | Overall [ORs (95% CI)] | CD [ORs (95% CI)] | UC [ORs (95% CI)] |
---|---|---|---|
Age (reference ≤40 years) | |||
41–60 years | 1.26 (0.92–1.73) | 1.62 (0.72–3.62) | 1.24 (0.87–1.78) |
>60 years | 1.00 (0.56–1.80) | 0.52 (0.06–4.24) | 1.05 (0.55–1.99) |
Gender (reference male) | |||
Female | 1.17 (0.82–1.68) | 1.12 (0.39–3.19) | 1.21 (0.81–1.82) |
Marital status (reference single) | |||
Married | 1.40 (1.00–1.92) | 1.45 (0.61–3.43) | 1.48 (1.01–2.17) |
Highest education (reference college or less) | |||
Bachelor’s degree | 0.79 (0.59–1.06) | 0.72 (0.32–1.66) | 0.73 (0.53–1.02) |
Master’s degree | 1.07 (0.61–1.89) | 0.94 (0.20–4.39) | 1.07 (0.56–2.02) |
Occupation | |||
Full time | 1.38 (0.47–4.01) | 0 (Omitted) | 0.97 (0.30–4.39) |
Part time | 1.13 (0.36–3.50) | 0 (Omitted) | 0.65 (0.19–2.26) |
Self-employed | 0.72 (0.23–2.27) | 0 (Omitted) | 0.62 (0.17–2.20) |
Housewife | 1.56 (0.50–4.86) | 0 (Omitted) | 0.99 (0.29–3.44) |
Student | 1.56 (0.16–14.72) | 0 (Omitted) | 0 (Omitted) |
Unemployed/pensioners | 1.70 (0.56–5.15) | 0 (Omitted) | 1.28 (0.37–4.39) |
Household incomes (reference less than 2 M JPY) | |||
2–4 M JPY | 1.41 (0.48–4.12) | 0 (Omitted) | 1.00 (0.31–3.26) |
4–6 M JPY | 1.13 (0.37–3.56) | 0 (Omitted) | 0.66 (0.19–2.31) |
6–8 M JPY | 0.73 (0.23–2.31) | 0 (Omitted) | 0.63 (0.18–2.27) |
8–10 M JPY | 1.58 (0.50–4.97) | 0 (Omitted) | 1.01 (0.29–3.54) |
More than 10 M JPY | 1.59 (0.17–15.10) | 0 (Omitted) | 0 (Omitted) |
Comorbidity | |||
Dyslipidemia | 1.82 (1.08–3.08) | 0.73 (0.10–5.08) | 1.66 (0.93–2.98) |
Hypertension | 0.95 (0.61–1.49) | 2.65 (0.47–15.09) | 0.83 (0.50–1.36) |
COPD asthma | 3.61 (1.41–9.26) | 0 (Omitted) | 2.26 (0.83–6.17) |
Diabetes | 0.59 (0.32–1.10) | 0 (Omitted) | 0.44 (0.22–0.88) |
Depression | 1.64 (0.91–2.96) | 1.10 (0.21–5.74) | 1.69 (0.87–3.30) |
OA and RA | 0.61 (0.12–3.16) | 0 (Omitted) | 1.00 (0.16–6.27) |
Gastrointestinal disease | 0.68 (0.34–1.34) | 0.11 (0.01–1.24) | 0.82 (0.39–1.75) |
Surgical history | |||
Previous surgical | 1.66 (1.13–2.42) | 1.49 (0.67–3.31) | 1.94 (1.12–3.36) |
Time since diagnosis (reference 0–2 years) | |||
3–8 years | 0.70 (0.46–1.08) | 0.54 (0.09–3.21) | 0.75 (0.46–1.18) |
9–15 years | 0.67 (0.42–1.07) | 0.30 (0.05–1.93) | 0.78 (0.47–1.29) |
>15 years | 0.79 (0.49–1.27) | 0.93 (0.15–5.56) | 0.71 (0.42–1.20) |
Current treatment | |||
Nutritional | 1.20 (0.82–1.75) | 1.50 (0.69–3.26) | 1.12 (0.66–1.91) |
5-ASA | 1.08 (0.72–1.63) | 1.25 (0.53–2.99) | 1.01 (0.60–1.72) |
Steroid | 1.40 (0.95–2.09) | 4.20 (0.98–17.98) | 1.18 (0.75–1.84) |
Immunosuppressant | 0.93 (0.62–1.41) | 0.64 (0.28–1.48) | 1.09 (0.65–1.82) |
Biologic agents | 1.76 (1.17–2.65) | 1.81 (0.78–4.23) | 1.89 (1.02–3.50) |
Cytapheresis | 1.61 (0.44–5.85) | 0 (Omitted) | 1.82 (0.49–6.78) |
Type of hospitals (reference university hospital) | |||
General/specialist hospital | 0.64 (0.46–0.90) | 1.06 (0.48–2.33) | 0.52 (0.35–0.78) |
Clinics | 0.61 (0.40–0.92) | 0.12 (0.02–0.57) | 0.61 (0.38–0.97) |
Frequency of visits (reference more than once in a month) | |||
Once every month | 0.85 (0.49–1.48) | 0.65 (0.16–2.66) | 1.02 (0.53–1.96) |
Once every 2 months | 0.90 (0.51–1.60) | 0.62 (0.15–2.56) | 1.09 (0.55–2.18) |
Once every 3 months | 1.06 (0.57–2.00) | 0.36 (0.69–1.92) | 1.41 (0.68–2.94) |
Less than every 3 months | 0.62 (0.30–1.30) | 0.13 (0.01–1.91) | 0.86 (0.36–2.01) |
CD Crohn’s disease, UC ulcerative colitis, COPD chronic obstructive pulmonary disease, OA osteoarthritis, RA rheumatoid arthritis, 5-ASA 5-aminosalicylic acid
Bold values indicate significance at 5% level or higher