Table 1.
Differences between mechanisms of action of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in relation to endothelial function and thrombosis risk [41]
ACEI | ARB | |
---|---|---|
Reduces endothelial dysfunction | + | + |
Reduces inflammation | + | − |
Reduces cell adhesion | + | + |
Antithrombotic effect | + | ± |
Anti-atherosclerotic effect | + | + |
Reduces cell apoptosis | + | − |
Strengthens fibrinolitic balance | + | ± |
ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker