Table 4.
Histological changes of the hearts (H&E) in the studied groups
| Sham | OVX | OVX.D | |
|---|---|---|---|
| Cardiac fibers hypertrophy | 0 | 6.60 ± 0.50* | 9.20 ± 0.37** |
| Myocardial fibrosis | 0 | 5.20 ± 0.58* | 9.00 ± 0.31** |
| Leukocyte Infiltration | 0 | 5.00 ± 0.37* | 7.80 ± 0.24** |
| Disorganization myocardial fibers disarray | 0 | 5.40 ± 0.60* | 9.40 ± 0.40** |
| Cardiomyocyte vacuolation | 0 | 5.00 ± 0.31* | 7.80 ± 0.37** |
| Cardiomyocyte degeneration | 0 | 4.80 ± 0.37* | 8.60 ± 0.50** |
| Cardiac nucleus eccentric | 0 | 5.00 ± 0.44* | 9.00 ± 0.44** |
A minimum of ten fields for each heart slide was examined and assigned for severity of injury based on numbers of 10 microscopic fields (n=10 for each group). Data are expressed as mean ± SEM. OVX: ovariectomized group, OVX.D: ovariectomized with 8-week diabetes group
*
P<0.05 vs sham & OVX.D
**
P<0.05 vs sham