Table 3.
FICs of K. pneumoniae strains for the antibiotics/Thymbra spicata extract combinations
| K.pneumoniae strains | FICs | AM | CTX | AMK | CIP | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (AQ) | (ET) | (PE) | (AQ) | (ET) | (PE) | (AQ) | (ET) | (PE) | (AQ) | (ET) | (PE) | ||
| MDR Kp1 | FIC (Ab) | 0.25 | 0.13 | 0.13 | 0.25 | 0.13 | 0.13 | 0.25 | 0.25 | 0.13 | 0.5 | 0.5 | 0.25 |
| FIC (Ts) | 0.25 | 0.13 | 0.25 | 0.25 | 0.13 | 0.25 | 0.5 | 0.25 | 0.5 | 0.5 | 0.5 | 1 | |
| ΣFIC | 0.5 | 0.26 | 0.38 | 0.5 | 0.26 | 0.38 | 0.75 | 0.5 | 0.63 | 1 | 1 | 1.25 | |
| MDR Kp2 | FIC (Ab) | 0.25 | 0.13 | 0.13 | 0.25 | 0.13 | 0.13 | 0.5 | 0.25 | 0.25 | 1 | 0.25 | 0.25 |
| FIC (Ts) | 0.25 | 0.13 | 0.13 | 0.25 | 0.25 | 0.25 | 0.5 | 0.5 | 1 | 1 | 0.5 | 0.5 | |
| ΣFIC | 0.5 | 0.26 | 0.26 | 0.5 | 0.38 | 0.38 | 1 | 0.75 | 1.25 | 1.5 | 0.75 | 0.75 | |
| MDR Kp3 | FIC (Ab) | 0.5 | 0.25 | 0.25 | 0.25 | 0.13 | 0.13 | 0.25 | 0.25 | 0.13 | 0.5 | 0.25 | 0.13 |
| FIC (Ts) | 0.25 | 0.25 | 0.25 | 0.5 | 0. 5 | 0.5 | 1 | 1 | 1 | 1 | 0.5 | 1 | |
| ΣFIC | 0.75 | 0.5 | 0.5 | 0.75 | 0.63 | 0.63 | 1.25 | 1.25 | 1.13 | 1.5 | 0.75 | 1.13 | |
| MDR Kp4 | FIC (Ab) | 0.25 | 0.13 | 0.13 | 0.25 | 0.13 | 0.13 | 0.5 | 0.5 | 0.25 | 0.5 | 0.25 | 0.25 |
| FIC (Ts) | 0.25 | 0.13 | 0.5 | 0.5 | 0.25 | 0.5 | 0.5 | 1 | 0.5 | 1 | 1 | 1 | |
| ΣFIC | 0.5 | 0.26 | 0.63 | 0.75 | 0.38 | 0.63 | 1 | 1.5 | 0.75 | 1.5 | 1.25 | 1.25 | |
| Sen. Kp5 | FIC (Ab) | 0.5 | 0.5 | 0.5 | 0.5 | 0.25 | 0.25 | 0.5 | 0.5 | 0.25 | 1 | 1 | 1 |
| FIC (Ts) | 0.5 | 0.5 | 1 | 0.5 | 0.5 | 1 | 0.5 | 0.5 | 1 | 1 | 1 | 1 | |
| ΣFIC | 1 | 1 | 1.5 | 1 | 0.75 | 1.25 | 1 | 1 | 1.25 | 2 | 2 | 2 | |
| ATCC 700603 | FIC (Ab) | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.5 | 0.25 | 0.25 | 1 | 1 | 1 |
| FIC (Ts) | 0.5 | 0.5 | 0.5 | 1 | 0.5 | 0.5 | 1 | 0.25 | 1 | 1 | 1 | 1 | |
| ΣFIC | 0.75 | 0.75 | 0.75 | 1.25 | 0.75 | 0.75 | 1.5 | 0.5 | 1.25 | 2 | 2 | 2 | |
Sa: Staphylococcus aureus, Kp: Klebsiella pneumoniae, AM: ampicillin, CEX: cefotaxime, AMK: amikacin, CIP: ciprofloxacin, AQ: aquaeous, ET: ethanol, PE: petroleum ether