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. 2016 Nov 1;6(11):2463–2475.

Figure 7.

Figure 7

Restoration of STMN1 abolishes the tumor suppressor role of miR-193b. A. The protein level of STMN1 was measured in HT29 and SW1116 cells transfected with either the control or miR-193b mimics along with either pcDNA3.1 or pcDNA3.1-STMN1. B. The effect of the miR-193b mimic on the proliferative potential of HT29 and SW1116 cells was detected in the presence of pcDNA3.1-STMN1 treatment via CCK-8 assays. C. The effect of the miR-193b mimic on the invasive potential of HT29 and SW1116 cells was detected in the presence of pcDNA3.1-STMN1 treatment via Transwell assays. The results are shown as the mean ± SEM (**P<0.01, ***P<0.001) of triplicate determination from three independent experiments.