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PCAIs inhibit human pancreatic cancer cell proliferation. Cultured MIAPaCa-2 (5,000 cells) and BxPC-3 (5000 cells) cells were treated with the indicated concentrations of PCAIs for 48 h and the cell proliferation was determined as described in the methods. The results are the means (± SEM, N = 4) and are representative of four independent experiments.
