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Upregulated expression of CCND1 or CCNE1 partly rescues the malignant phenotypes in FAM83D-knockdown cells. A. Transfection efficiency of upregulating CCND1 and CCNE1 was determined using qRT-PCR and western blot. B and C. Upregulation of either CCND1 or CCNE1 partly rescued the proliferative and colony formative abilities in FAM83D-knockdown cells. D. Upregulation of either CCND1 or CCNE1 alleviated the G1 phase arrest of FAM83D-knockdown cells. *P<0.01.
