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. 2016 Nov 1;6(11):2641–2650.

Figure 4.

Figure 4

G3BP1 upregulates Slug expression. A. The expression levels of tumor-related factors were detected by western blotting in Sk-Hep1/LV-shNC, Sk-Hep1-1/LV-shG3BP1 and WRL68/LV-shNC, WRL68/LV-shG3BP1 cells. G3BP1 silencing decreased the expression of Slug on protein level. B. Knocking down G3BP1 increased the expression of E-cadherin in mRNA level in above cells. C. G3BP1 knockdown suppressed the expression of Slug and upregulated the expression of E-cadherin in Huh7 cells by western blotting. D and E. The expression of G3BP1 and Slug in G3BP1 stably silenced HCC cells as indicated by qRT-PCR analysis. *P<0.05, **P<0.01.