Table 3.

Result of a survival analysis with Cox’s proportional hazard model

	Univariatea	Multivariateb
	P-value	HRc	95% CId	P-value
Sex
Male vs Female	0.9427		-
Age
≥65 vs <65	0.7749	2.74	1.134-6.967	0.0250
Siewert type
Type2 vs Type3	0.8131		-
Histological type
Undiffe. vs Diffe.	0.0486		-
Tumor size (mm)
≥40 vs <40	0.0185		-
Venous invasion
Positive vs Negative	<0.0001		-
Lymphatic invastion
Positive vs Negative	<0.0001	5.28	1.431-25.51	0.0116
PT-stage
T4 vs T1-3	<0.0001	4.74	2.004-12.21	0.0003
PN-stage
N3 vs N0-2	<0.0001	3.28	1.354-8.607	0.0081
YWHAZ expression
High vs Low	0.0108	4.49	1.736-13.06	0.0015

^aKaplan and Meier method, and the statistical significance was determined by log-rank test;

^bMultivariate survival analysis was performed using Cox’s proportional hazard model;

^cHR: hazard ratio;

^dCI: confidence interval.