Table 3.
Diagnostic test characteristics of LS values from 2D-MRE in detection of liver fibrosis staging
| ≥F1 | ≥F2 | ≥F3 | F4 | |
|---|---|---|---|---|
| Cut-off (kPa) | 1.11 | 1.37 | 1.69 | 2.03 |
| AUC | 0.96 ± 0.03 | 0.95 ± 0.02 | 0.99 ± 0.01 | 0.994 ± 0.01 |
| Sensitivity (%) | 97.4 | 92.6 | 94.7 | 100 |
| Specificity (%) | 80.0 | 92.3 | 97.1 | 97.6 |
| Accuracy (%) | 92.5 | 92.5 | 96.2 | 98.1 |
| PPV (%) | 92.5 | 92.6 | 94.7 | 92.3 |
| NPV (%) | 92.3 | 92.3 | 97.1 | 88.9 |
| F-value | 42.59 | 29.63 | 19.79 | 12.473 |
| P-value | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 |
LS, liver stiffness; AUC, areas under the ROC curve; PPV, Positive predictive value; NPV, Negative predictive value.